Baltimore Orioles at Houston Astros Odds, Picks and Predictions

THE Baltimore Orioles (49-26) and Houston Astros (36-40) play the second game of their 3-game series on Saturday. First pitch from Minute Maid Park is scheduled for 4:10 p.m. ET. Let’s analyze the FanDuel Sportsbook lines around the Orioles vs. Astros odds and make our expert MLB picks and predictions for the best bets.

Seasonal series: Astros lead 1-0

The Orioles are in the middle of a 6-game road trip, which started with a 2-of-3 win over the New York Yankees. However, they lost the first game of this series on Friday 14-11 despite being -150 favorites; the Astros conceded +138 dogs at home. Baltimore SP Grayson Rodriguez (5 IP, 7 ER, 9 H, 1 HR, 2 BB, 8 K) suffered his first defeat in June after a 3-0 start to the month. SS Gunnar Henderson parked his 23rd and 24th home runs of the season and C Adley Rutschman The breakout season continued with a 5-for-5 night in defeat, improving his batting average to .305.

Friday’s victory was Houston’s third in a row. Astros’ huge offensive night was led by 2B Jose Altuve going 3-for-5 with 2 doubles, 2 RBIs and 2 runs. L.F. Joey Loperfido also had 3 hits, while 3B Alex Bregman1B Jon Singleton and SS Mauricio Dubon each had 2 hits, and CF Jake Meyers hitting a 3-point jack.

Orioles at Astros projected starters

RHP Corbin Burnes against RHP Ronel Blanco

Burnes (8-2, 2.14 ERA) is making his 16th start. He has a WHIP of 1.04, 2.3 BB/9 and 8.6 K/9 in 92 2/3 innings.

• Last start: Win, 6 IP, 2 ER, 7 H, 2 BB, 7 K in an 8-3 home win over the Philadelphia Phillies on Sunday
• Didn’t lose in June — 3-0, 1.35 ERA (20 IP, 3 ER) in 3 starts
• 2024 road splits: 4-1, 2.54 ERA (39 IP, 11 ER), 0.95 WHIP, 7.6 K/9 in 6 starts
• Career vs. Astros: 0-1, 7.50 ERA (6 IP, 5 ER) in 1 start and 1 relief appearance

Blanco (7-2, 2.43 ERA) is making his 14th start. He has a 0.96 WHIP, 3.6 BB/9 and 8.7 K/9 in 77 2/3 innings.

• Last Start: Win, 7 IP, 0 ER, 0 H, 3 BB, 8 K in a 4-1 win over the Detroit Tigers on Sunday
• 2024 Home Splits: 2-2, 2.83 ERA (41 1/3 IP, 13 ER), 0.92 WHIP, 8.3 K/9 in 7 starts
• I’ve never faced the Orioles before

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Orioles at Astros odds

Powered by FanDuel Sportsbook; Go to the USA TODAY Sports Sports Betting Scores & Odds hub for a complete list. Lines were last updated at 5 a.m. ET.

• Money Line (ML): Orioles -154 (bet $154 to win $100) | Astros +130 (bet $100 to win $130)
• Running Line (RL)/Against the Spread (ATS): Orioles -1.5 (+112) | Astros +1.5 (-134)
• More/Less (Y/U): 7.5 (O: -122 | U: +100)

Orioles picks and predictions at Astros

Prediction

Orioles 3, Astros 2

Money line.

PASS.

The Orioles (-154) won Saturday afternoon after failing to come back Friday evening. As much as I like Baltimore to win, I’m not interested in betting just over 1½ units with the -154 ML for that to happen. I’m saving my bet for the racing line.

Running Line/Against the Spread

ORIOLES BET -1.5 (+112).

The Astros are perhaps the most disappointing team in the majors, essentially playing .500 baseball over the past 30 days. Blanco has been the lone bright spot in their rotation, but he has struggled in 2 of his last 3 starts at home.

The Orioles are road warriors with an MLB-best record of 24-12 away from home. On top of that, they had their ace on the mound Saturday. Burnes has only allowed 3 earned runs in his last 4 starts (27 IP). He hasn’t lost since 8 starts ago on May 7th. Baltimore’s pitching staff has a 3.08 ERA on the road and their opponents are hitting just .202 against them.

More less

BET UNDER 7.5 (+100).

The Astros have been struggling to score runs lately. The Under has hit in 4 of their last 5 games and in 7 of their last 10. It won’t get any easier with Burnes taking the mound for the Orioles.

Meanwhile, the Under is 10-0 in Blanco’s last 10 starts and 11-2 in his 13 starts this season.

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