San Francisco Giants at Arizona Diamondbacks Odds, Picks, Predictions

The San Francisco Giants (79-79) and Arizona Diamondbacks (87-71) ends their 3-game hitting streak and season series on Wednesday. First pitch at Chase Field is at 9:40 PM ET (MLB Network). Let’s look at BetMGM Sportsbook’s MLB odds around Giants vs. Diamondbacks odds and make our expert MLB picks and predictions for the best bets.

Season series: tied 6-6

The Giants have won the first 2 games of the series (6-3 and 11-0) and are on a 5-game winning streak. They shut out Arizona on Tuesday night behind the starter Logan Webb. (6 IP, 0 ER, 4 H, 1 BB, 4 K).

The Diamondbacks have lost 3 in a row and have a half-game lead over the Atlanta Braves for the final NL Wild Card. I’m tied in the loss column with them. They are a half game behind the New York Mets for the 2nd Wild Card spot.

The Diamondbacks’ Giants drafted rookies

RHP Mason Black against RHP Zach Gallen

Black (1-4, 5.88 ERA) is making his 8th start and 9th career appearance. He has a 1.52 WHIP, 2.7 BB/9 and 7.5 K/9 in 33 2/3 IP.

• Last start: Win, 5 2/3 IP, 0 R, 4 H, 1 BB, 4 K in 2-1 road win over Kansas City Royals on Friday
• Face Arizona for the first time

Gallen (13-6, 3.74 ERA) is making his 28th start. He has a WHIP of 1.29, 3.3 BB/9 and 9.2 K/9 in 142 IP.

• Last start: Win, 5 IP, 4 ER, 7 H, 1 BB, 5 K in 7-4 road win vs. Milwaukee Brewers on Friday
• He is 3-0 with a 3.00 ERA in Sept. 4 starts
• Vs. Giants: Is 1-1 with 4.09 ERA in 2 starts in 2024 and 5-5 with 4.15 ERA in 15 career starts

Who goes to the yard? Here’s a breakdown of today’s the best home run items with our top picks. Include BetMGM bonus code SBWIRE to get a first bet offer of $1,500.

Giants at Diamondbacks odds

Provided by BetMGM Sportsbook; visit the USA TODAY sports scores and sports betting odds center for a complete list of MLB odds. Lines last updated at 9:21 am ET.

• Money Line (ML): Giants +185 (bet $100 to win $185) | Diamondbacks -225 (bet $225 to win $100)
• Run line (RL)/Against the spread (ATS): Giants +1.5 (-110) | Diamondbacks -1.5 (-110)
• Over/Under (O/U): 8.5 (O: -110 | U: -110)

Giants at Diamondbacks picks and predictions

foresight

Diamondbacks 7, Giants 3

Moneyline

The Diamondbacks haven’t been swept in a home series yet this season. And while the Giants are 7-1 on their current road trip, Black has allowed 4 or more runs in 4 of his 8 appearances this season.

Arizona has won Gallen’s last 4 starts and should win, but don’t bet the money line at -225

PASHA.

Run line/Against the spread

Sixteen of the Diamondbacks’ last 18 wins have been by 2 or more runs. Five of Arizona’s last 6 wins when Gallen’s pitches were 2 or more runs. Five of their six wins against the Giants this season have been by 2 or more runs.

BET DIAMONDS -1.5 (-110).

Over/Under

Eight of the 12 meetings this season have totaled more than 8 runs and 6 of the Diamondbacks’ last 8 games have had 9 or more runs.

BET OVER 8.5 (-110).

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