The Toronto Blue Jays face the Houston Astros on Wednesday

Houston Astros (43-42, second in the AL West) at Toronto Blue Jays (39-46, fifth in the AL East)

Toronto; Wednesday, 7:07 p.m. EDT

Pitching Probables: Astros: Ronel Blanco (8-3, 2.49 ERA, 1.01 WHIP, 84 strikeouts); Blue Jays: Yusei Kikuchi (4-8, 4.18 ERA, 1.31 WHIP, 93 strikeouts)

:LINE Astros -113, Blue Jays -107; over/under is 8 1/2 points

IN BRIEF: The Toronto Blue Jays host the Houston Astros on Wednesday.

Toronto is 21-22 at home and 39-46 overall. The Blue Jays are 27-15 in games where they have eight or more hits.

Houston is 19-23 away from home and 43-42 overall. Astros hitters have a .322 on-base percentage, the second-highest in the American League.

Wednesday’s game is the sixth meeting between the two teams this season. The Astros have a 3-2 advantage in the season series.

TOP PERFORMERS: Vladimir Guerrero Jr. leads the Blue Jays with a .298 batting average and has 18 doubles, 13 homers, 39 walks and 50 RBIs. Isiah Kiner-Falefa is 16-for-38 with three homers and four RBIs over the last 10 games.

LAST 10 GAMES: Blue Jays: 4-6, .248 batting average, 5.69 ERA, outscored by six runs

Astros: 8-2, .293 batting average, 3.70 ERA, have outscored opponents by 27 runs

INJURIES: Blue Jays: Isiah Kiner-Falefa: 10 days on the disabled list (knee), Vladimir Guerrero Jr.: day to day (finger), Yimi Garcia: 15 days on the disabled list (elbow), Jordan Romano: 15 days on the disabled list (elbow), Alek Manoah: 15 days on the disabled list (elbow)

Astros: Jake Bloss: 15 days on injured list (shoulder), Victor Caratini: 10 days on injured list (hip), Justin Verlander: 15 days on injured list (neck), Cristian Javier: 60 days on injured list (forearm), Kyle Tucker: 10 days on injured list (shin), Jose Urquidy: 60 days on injured list (forearm), Oliver Ortega: 60 days on injured list (elbow), Bennett Sousa: 60 days on injured list (shoulder), Penn Murfee: 60 days on injured list (elbow), Luis Garcia: 60 days on injured list (elbow), Lance McCullers Jr.: 60 days on injured list (elbow), Kendall Graveman: 60 days on injured list (elbow)

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The Associated Press created this story using technology provided by Data Skrive and data from Sportradar.