Odds, predictions and predictions for Cleveland Guardians vs Chicago White Sox

THE Cleveland Goalies (82-62) and The Chicago White Sox (33-112) will play the middle game of a 3-game series on Tuesday. First pitch from Guaranteed Rate Field is scheduled for 7:40 p.m. ET. Let’s analyze the lines from FanDuel Sportsbook around the The Guardians vs. the White Sox odds and make our expert MLB picks and predictions for the best bets.

Season Series: Guardians lead 6-5

The Guardians took a 5-3 win in the series opener on Monday. Cleveland took a 5-0 lead after 5 innings, while Chicago scored 3 runs in the bottom of the 7th and 8th to make the game interesting. However, the Guards held on to cover the run line (-1.5, -140).

The White Sox have been terrible all season, but especially lately. Since August 23, Chicago has lost 15 of its last 17 games, and 13 of those losses have been by 2 runs or more.

As for the totals, Chicago has won 3 of the last 4 games, while the Under is 9-4 in the previous 13 outings. For Cleveland, the Under is 4-0-1 in the last 5 games and 7-0-2 in the previous 9 games.

White Sox goalies plan to play with their starters

RHP Ben Lively against RHP Jonathan Cannon

Lively (11-9, 4.07 ERA) is making his 26th start. He has a 1.25 WHIP, 2.9 BB/9 and 7.2 K/9 in 135 innings.

• Last Start: Loss, 4 innings, 4 earned runs, 7 hits (1 home run), 1 BB, 3 strikeouts in a 4-1 road loss to the Kansas City Royals last Wednesday
• 2024 Away Divisions: 4-7, 4.19 ERA, 68 2/3 IP, 32 ER, 12 HR, 1.27 WHIP, .246 opponents batting average (OBA), 23 BB, 59 K in 13 starts
• Career vs. White Sox: 1-1, 4.63 ERA, 11 2/3 IP, 6 ER, 1 HR, 1.54 WHIP, 6.2 K/9 in 2 starts

Cannon (3-9, 4.53 ERA) is making his 18th start and 20th appearance. He has a 1.39 WHIP, 2.9 BB/9 and 6.2 K/9 in 101 1/3 IP.

• Last Start: Win, 5 2/3 IP, 1 ER, 5 H (1 solo HR), 1 BB, 4 K in an 8-1 road win over the Baltimore Orioles last Wednesday
• 2024 Home Divisions: 1-4, 4.17 ERA, 54 IP, 25 ER, 8 HR, 1.31 WHIP, .242 OBA, 21 BB, 36 K in 10 appearances (8 starts)
• Never faced the Guardians

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Guardians vs. White Sox

Powered by FanDuel Sportsbook; go to the USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Odds last updated at 6:36 a.m. ET.

• Moneyline (ML): Guardians -220 (bet $220 to win $100) | White Sox +184 (bet $100 to win $184)
• Running Line (RL)/Against the Spread (ATS): Guardians -1.5 (-142) | White Sox +1.5 (+118)
• More/Less (O/U): 8.5 (O: -102 | U: -120)

Guardians White Sox picks and predictions

Prediction

Guardians 4, White Sox 3

Money line

The Guardians (-220) will cost you more than 2x your potential return against the hapless White Sox (+184). This will be a close game like Monday’s series opener. Cleveland cruised to a 5-3 victory, but Chicago didn’t give up, scoring 3 runs against the Guardians bullpen in the late innings to make things interesting. Expect another close game, as rookie Cannon hasn’t been too bad.

PASS.

Racing Line/Against the Spread

THE WHITE SOX +1.5 (+118) are worth playing in Tuesday’s mid-game with extra money.

Chicago has Cannon on the mound, and he’s been pretty consistent at times. The White Sox have won 2 of their last 5 games, which is pretty good for them. And, against the Guardians, the White Sox are surprisingly competitive at 5-6. Take the ChiSox to cover as underdogs on the run line.

More/Less

LESS THAN 8.5 (-120) is the best game on the board

The total has dropped to a 9-4 pace over the last 13 outings for the White Sox, and the total has dropped to a 7-0-2 pace over the last 9 outings for the Guardians. Additionally, the Under has conceded in 4 of the last 5 games of the series. Lively and Cannon are also capable of keeping the scores low early in games.

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